Asked by Heidi Jackeline on May 13, 2024

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What is the effective number exposed to risk of dying in the 13- to 24-month interval? Use the following table to answer the question. Survival of Patients With Metastatic Cancer Z Following Diagnosis
 Interval  since  beginning  treatment  (months)   Alive at  beginning  of  interval  Died  during  interva 1 Withdre  w during  interval  Effective  number  exposed  to risk of  dying  Proporti  on who  died  during  interval  Proportion  who did not  die during  interval  Cumulative  proportion  who  survived  from  enrollment  to end of  interval xIxdxWxIx′qxpxPx1−12200104013−24150203025−36100302037−48504010\begin{array}{|l|l|l|l|l|l|l|l|}\hline \begin{array}{l}\text { Interval } \\\text { since } \\\text { beginning } \\\text { treatment } \\\text { (months) }\end{array} & \begin{array}{l}\text { Alive at } \\\text { beginning } \\\text { of } \\\text { interval }\end{array} & \begin{array}{l}\text { Died } \\\text { during } \\\text { interva } \\1\end{array} & \begin{array}{l}\text { Withdre } \\\text { w during } \\\text { interval }\end{array} & \begin{array}{l}\text { Effective } \\\text { number } \\\text { exposed } \\\text { to risk of } \\\text { dying }\end{array} & \begin{array}{l}\text { Proporti } \\\text { on who } \\\text { died } \\\text { during } \\\text { interval }\end{array} & \begin{array}{l}\text { Proportion } \\\text { who did not } \\\text { die during } \\\text { interval }\end{array} & \begin{array}{l}\text { Cumulative } \\\text { proportion } \\\text { who } \\\text { survived } \\\text { from } \\\text { enrollment } \\\text { to end of } \\\text { interval }\end{array} \\\hline x & I_{x} & d_{x} & W_{x} & I_{x}^{\prime} & q_{x} & p_{x} & P_{x} \\\hline 1-12 & 200 & 10 & 40 & & & & \\\hline 13-24 & 150 & 20 & 30 & & & & \\\hline 25-36 & 100 & 30 & 20 & & & & \\\hline 37-48 & 50 & 40 & 10 & & & & \\\hline\end{array} Interval  since  beginning  treatment  (months)  x112132425363748 Alive at  beginning  of  interval Ix20015010050 Died  during  interva 1dx10203040 Withdre  w during  interval Wx40302010 Effective  number  exposed  to risk of  dying Ix Proporti  on who  died  during  interval qx Proportion  who did not  die during  interval px Cumulative  proportion  who  survived  from  enrollment  to end of  interval Px

A) 40
B) 90
C) 120
D) 135
E) 160

Effective Number

A statistical concept that represents the number of units in a dataset that contribute information to a particular analysis, often used in the context of sample size or diversity.

Risk of Dying

The probability or chance of an individual dying from a specific cause or in a given time period.

Metastatic Cancer

Cancer that has spread from the primary site of origin to different areas of the body through the lymph system or bloodstream.

  • Calculate the effective number exposed to the risk of dying in survival analysis.
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UI
uzair imranMay 15, 2024
Final Answer :
D
Explanation :
The effective number exposed to risk of dying in the 13- to 24-month interval can be calculated using the formula: Ix′=Ix−12WxI_x^{\prime} = I_x - \frac{1}{2}W_xIx=Ix21Wx , where IxI_xIx is the number alive at the beginning of the interval and WxW_xWx is the number who withdrew during the interval. For the 13-24 month interval, Ix=150I_x = 150Ix=150 and Wx=30W_x = 30Wx=30 , so Ix′=150−12(30)=150−15=135I_x^{\prime} = 150 - \frac{1}{2}(30) = 150 - 15 = 135Ix=15021(30)=15015=135 .