The two MOST common drugs used by adolescents are:

A) inhalants and alcohol.
B) tobacco and alcohol.
C) marijuana and alcohol.
D) prescription drugs and tobacco.

Marijuana and alcohol are the two most commonly used substances by adolescents. Studies consistently show that these two substances are the most prevalent among teenagers, followed by tobacco and prescription drugs. Inhalant use is also a concern, but it is not as common as the use of marijuana and alcohol.