Asked by sidorela mjeshtri on Sep 23, 2024
Verified
Which of the following reagents are commonly used to acylate the amino group of an amino acid?
A) both acetic anhydride and benzyl chloroformate
B) both benzyl chloroformate and α-bromoacetic acid
C) both α-bromoacetic acid and tosyl chloride
D) both tosyl chloride and acetic anhydride
E) both benzyl chloroformate and tosyl chloride
Amino Group
A functional group consisting of a nitrogen atom attached by single bonds to hydrogen atoms, alkyl groups, or aryl groups.
Amino Acid
Organic compounds containing an amine group, a carboxylic acid group, and a side chain that varies between different amino acids, key building blocks of proteins.
- Differentiate between reagents used in amino acid acylation.
Verified Answer
ER
Elena Reyes5 days ago
Final Answer :
A
Explanation :
Acetic anhydride and benzyl chloroformate are commonly used reagents for acylating the amino group of an amino acid. Acetic anhydride introduces an acetyl group, while benzyl chloroformate is used for the introduction of a carbobenzyloxy (Cbz) protecting group.
Learning Objectives
- Differentiate between reagents used in amino acid acylation.