Asked by Erika Garcia on Sep 22, 2024

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A total of 1,500 pairs of adult twins,600 monozygotic and 900 dizygotic,were studied to estimate the concordance for a childhood cancer.In the 600 monozygotic twins,40 of the pairs were concordant for the disease,60 of the pairs were discordant for the disease,and neither twin had the disease in the remaining 500 pairs.In the 900 dizygotic twins,30 of the pairs were concordant for the disease,120 of the pairs were discordant for the disease,and neither twin had the disease in the remaining 750 pairs.What is the concordant rate,in monozygotic twins,of the disease in twin pairs with at least one affected member?

A) 0.1
B) 0.4
C) 0.6
D) 0.7
E) 1.5

Concordance Rate

The probability that two individuals with a shared genetic background will both exhibit a specific trait or disease.

Dizygotic Twins

Twins that are born from two separate eggs fertilized by two different sperm, also known as fraternal twins.

Childhood Cancer

encompasses the various types of cancer that occur in children, often presenting unique challenges due to the impact on growth, development, and treatment outcomes.

  • Comprehend the concepts of concordance and discordance rates in genetic studies involving twins.
  • Interpret the findings of twin studies to infer genetic contributions to diseases.
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DM
Dumza Mokano8 days ago
Final Answer :
B
Explanation :
The concordant rate of the disease in twin pairs with at least one affected member among monozygotic twins is 40,the number of pairs with concordant,divided by 100,40 plus 60,the total number of pairs with at least one affected member.The concordant rate equals 0.4.