Asked by Falak Dugla on Apr 24, 2024
Verified
An application of capsaicin to the skin or muscles causes first a burning sensation and then a prolonged decrease in pain sensations. Why?
A) At first capsaicin increases the flow of sodium across the membranes of pain neurons, but eventually the body runs out of sodium ions.
B) Capsaicin releases the pain neurotransmitter, substance P, faster than it can be resynthesized.
C) At first capsaicin damages endorphin synapses, but later they recover.
D) Capsaicin stimulates blood flow to the skin or muscles, but also prevents the blood from leaving the area.
Capsaicin
A chemical compound found in chili peppers that generates the sensation of heat or burning in any tissue with which it comes in contact.
Sodium Ions
Positively charged particles of sodium, which play crucial roles in the body such as maintaining fluid balance, transmitting nerve impulses, and muscle contraction.
Substance P
A neuropeptide involved in the transmission of pain and other sensory information to the central nervous system.
- Gain an understanding of the biochemical underpinnings of pain mitigation and the significance of neurotransmitters including endorphins and substance P.
- Acquire knowledge about the chemical and neurotransmitter activities associated with sensation and perception, including the experiences of itch and pain.
Verified Answer
Learning Objectives
- Gain an understanding of the biochemical underpinnings of pain mitigation and the significance of neurotransmitters including endorphins and substance P.
- Acquire knowledge about the chemical and neurotransmitter activities associated with sensation and perception, including the experiences of itch and pain.
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