Asked by Makell Brown on May 09, 2024

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Once cytotoxic T cells are produced, which of the following is/are consistent with their ability to attack intracellular viruses?

A) Most nucleated cells process antigens through the MHC class I mechanisms.
B) Viral antigens are processed by the MHC class I mechanism and are presented to the cell surface.
C) Cytotoxic T cells bind to MHC class I processed antigens.
D) Cytotoxic T cells bound to the MHC class I processed antigens release lymphokines.
E) All of the choices are correct.

Cytotoxic T cells

A type of immune cell that kills cancer cells, cells that are infected with viruses, or cells that are damaged in other ways.

MHC class I

Molecules found on the surface of all nucleated cells that present peptide fragments derived from the cell's internal proteins to the immune system.

Intracellular Viruses

Viruses that exist and replicate inside the cells of a host organism.

  • Describe the mechanisms through which cytotoxic T cells target and attack intracellular pathogens.
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TP
Tabatha ParrentMay 10, 2024
Final Answer :
E
Explanation :
Cytotoxic T cells recognize and attack infected cells by binding to viral antigens presented on the cell surface via MHC class I molecules. All nucleated cells present antigens through MHC class I mechanisms, allowing cytotoxic T cells to target cells infected with intracellular pathogens, including viruses. Upon recognition, cytotoxic T cells release substances like perforin and granzymes (rather than lymphokines, which are more commonly associated with helper T cells) to kill the infected cells, but the overall process described is consistent with their function.