Asked by Carlye Norris on Mar 10, 2024
Verified
Parathyroid hormone (PTH) causes
A) increased RANKL and increased OPG.
B) increased RANKL and decreased OPG.
C) decreased RANKL and increased OPG.
D) decreased RANKL and decreased OPG.
E) PTH has no effect on RANKL and OPG.
Parathyroid Hormone (PTH)
A hormone produced by the parathyroid glands that regulates calcium levels in a person's body.
RANKL
RANKL is a signaling molecule that plays a critical role in bone remodeling by activating osteoclasts, cells responsible for bone resorption.
OPG
Osteoprotegerin, a cytokine receptor involved in the regulation of bone density by inhibiting osteoclast differentiation and activation.
- Understand the influence of certain hormones on calcium homeostasis and the metabolism of bone.
Verified Answer
EV
Evangelina VasquezMar 10, 2024
Final Answer :
B
Explanation :
Parathyroid hormone (PTH) increases RANKL and decreases OPG to stimulate osteoclasts and increase bone resorption, thereby increasing blood calcium levels.
Learning Objectives
- Understand the influence of certain hormones on calcium homeostasis and the metabolism of bone.