The phenomenon that can produce high frequencies of deleterious alleles in small, isolated populations is

A) antigenic shift.
B) the founder effect.
C) natural selection.
D) resistance.

Deleterious Alleles

Genetic variants that negatively affect the fitness or survival of an organism, often leading to disease or reduced lifespan.

Founder Effect

A reduction in genetic variation that occurs when a new population is established by a very small number of individuals from a larger population.

Isolated Populations

Groups of organisms that are separated from exchanging genetic material with other organisms of the same species, often leading to speciation.