Asked by Angela DiFilippi on Sep 23, 2024

verifed

Verified

The reaction of LDA with acetophenone produces ________.

A) an enol
B) an enolate
C) an ylide
D) alkylation
E) halogenation

LDA

Lithium diisopropylamide, a strong, non-nucleophilic base used in organic synthesis to deprotonate weak acids.

Acetophenone

A colorless, viscous liquid used in fragrances and as a solvent, characterized by a sweet, pungent smell, belonging to the ketone family.

Enolate

An anion formed by the removal of an alpha hydrogen from a carbonyl compound by a base, creating a carbon-nitrogen double bond adjacent to a carbonyl group.

  • Understand the configuration and chemical behavior of lithium diisopropylamide (LDA) when utilized as a potent base in the domain of organic synthesis.
  • Comprehend the process of enolization along with the circumstances that facilitate its occurrence.
verifed

Verified Answer

ZH
Zukiswa Hlathini6 days ago
Final Answer :
B
Explanation :
LDA (lithium diisopropylamide) is a strong base that deprotonates the α-carbon of acetophenone to produce an enolate ion. Therefore, the best choice is B, an enolate.