Asked by Jordan Chipley on Sep 23, 2024

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Treatment of a peptide which contains disulfide linkages with peroxyformic acid yields a peptide which contains what new amino acid residue?

A) cystine
B) cysteic acid
C) 4-hydroxyproline
D) γ-alanine
E) methioic acid

Disulfide Linkages

Chemical bonds formed by the oxidation of two thiol groups, often important in the tertiary and quaternary structures of proteins.

Peroxyformic Acid

An organic compound that is a peroxy acid, formed by reacting formic acid with hydrogen peroxide, known for its oxidizing properties.

Cysteic Acid

An amino acid derived from the oxidation of cysteine, characterized by a sulfonic acid group (-SO3H) attached to its side chain.

  • Explain the operational mechanisms of certain chemical and enzyme reactions that occur in peptide and protein chemistry.
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SN
Sumeet Narangabout 5 hours ago
Final Answer :
B
Explanation :
Peroxyformic acid can oxidize cysteine residues in a peptide to cysteic acid, which contains a carboxylic acid group in addition to the thiol group present in cysteine. Therefore, the treatment would result in the addition of cysteic acid residues to the peptide, not a new amino acid residue.