What is the role of glial cells for pain perception

A)  If spinal glial cells are activated, they can reduce the experience of pain. 
B)  If glial cells are damaged or inactive, perception of pain increases. 
C)  Glial cells in the spinal cord appear to block transmission of endorphins to the periaqueductal grey. 
D)  Spinal glial cells are activated by the immune system and may amplify chronic pain.

Glial Cells

Non-neuronal cells in the central nervous system that support, protect, and nourish neurons, playing key roles in neural health and function.

Pain Perception

The individual's experience and interpretation of pain, which involves sensory, emotional, and cognitive components and can vary widely among individuals.

Chronic Pain

Persistent pain that extends beyond the usual course of an acute illness or healing of an injury, often lasting for months or years.