When caring for the child with Kawasaki disease, the nurse should know which information?

A) A child's fever is usually responsive to antibiotics within 48 hours.
B) The principal area of involvement is the joints.
C) Aspirin is contraindicated.
D) Therapeutic management includes administration of gamma globulin and aspirin.

High-dose IV gamma globulin and aspirin therapy is indicated to reduce the incidence of coronary artery abnormalities when given within the first 10 days of the illness. The fever of Kawasaki disease is unresponsive to antibiotics and antipyretics. Mucous membranes, conjunctiva, changes in the extremities, and cardiac involvement are seen. Aspirin is part of the therapy.