Asked by Shannon Leigh on Sep 27, 2024
When the carbonyl group of a neutral ketone is protonated ________.
A) the resulting species becomes more electrophilic
B) the resulting species is activated toward nucleophilic attack
C) subsequent nucleophilic attack on the resulting species is said to occur under acid-catalyzed conditions
D) the resulting species has a positive charge
E) all of the above
Carbonyl Group
A functional group consisting of a carbon atom double-bonded to an oxygen atom (C=O) found in aldehydes, ketones, carboxylic acids, and esters.
Electrophilic
Describes a chemical species that is attracted to electrons and tends to accept electrons during chemical reactions.
Nucleophilic Attack
The process by which a nucleophile forms a bond with a positive or partially positive atom in another molecule.
- Explain the effects of protonation on the electrophilicity and reactivity of carbonyl groups.
Learning Objectives
- Explain the effects of protonation on the electrophilicity and reactivity of carbonyl groups.
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