Asked by Shannon Leigh on Sep 27, 2024

When the carbonyl group of a neutral ketone is protonated ________.

A) the resulting species becomes more electrophilic
B) the resulting species is activated toward nucleophilic attack
C) subsequent nucleophilic attack on the resulting species is said to occur under acid-catalyzed conditions
D) the resulting species has a positive charge
E) all of the above

Carbonyl Group

A functional group consisting of a carbon atom double-bonded to an oxygen atom (C=O) found in aldehydes, ketones, carboxylic acids, and esters.

Electrophilic

Describes a chemical species that is attracted to electrons and tends to accept electrons during chemical reactions.

Nucleophilic Attack

The process by which a nucleophile forms a bond with a positive or partially positive atom in another molecule.

  • Explain the effects of protonation on the electrophilicity and reactivity of carbonyl groups.