Which of the following compounds is least reactive in the nucleophilic aromatic substitution reaction with NaOH?

A) 2,4-dinitrochlorobenzene
B) m-nitrochlorobenzene
C) o-nitrochlorobenzene
D) p-nitrochlorobenzene
E) 3,5-dinitrochlorobenzene

Nucleophilic Aromatic Substitution

A reaction where an electron-rich nucleophile displaces a leaving group in an aromatic ring, typically under conditions where the aromatic ring is activated towards nucleophilic attack.

2,4-Dinitrochlorobenzene

A chemical compound characterized by a benzene ring with two nitro groups (NO2) and one chlorine atom attached to it at the 2, 4, and 6 positions, respectively.

NaOH

Sodium hydroxide, a strong base used in both industry and laboratories.