Which of the following is true of Phase I clinical trials?

A) They are designed to determine dosage, toxicity, and side effects.
B) They rely solely on animals as test subjects.
C) They are not required by the FDA.
D) They are the last stage of clinical testing.

Phase I Clinical Trials

The first stage of clinical trials for new drugs or treatments, primarily concerned with assessing safety and dosage in a small group of people.

Dosage

Dosage refers to the size, frequency, and number of times a medication or drug should be taken to achieve its intended effect.

Toxicity

The degree to which a substance can cause harm to an organism, ranging from mild irritation to lethal effects.