Which of the following processes help(s) to explain the high incidence of certain rare genetic diseases in the Amish?

A) bottlenecks
B) inbreeding
C) natural selection
D) a and b
E) a, b, and c

Rare Genetic Diseases

Disorders caused by changes in genes or chromosomes, often with low prevalence in the general population but with significant impacts on those affected.

Bottlenecks

Events that drastically reduce the size of a population, leading to loss of genetic variation and increasing the influence of genetic drift.

Inbreeding

The breeding or mating of closely related individuals, which can lead to an increased chance of offspring inheriting genetic disorders or traits.