Asked by Malusi Pakade on May 17, 2024
Verified
Which statement best describes a threshold dose-response model?
A) It implies there is a dose below which no detectable harmful effects occur.
B) It implies that each dose of ionizing radiation or toxic chemical carries a risk of causing harm.
C) It is useful for assessing chronic toxicity.
D) It errs on the side of safety.
Threshold Dose-Response
A concept in toxicology that indicates the lowest dose at which a particular response or effect is observed in an organism or system.
Ionizing Radiation
A type of energy released by atoms in the form of electromagnetic waves or particles that is capable of removing electrons from atoms or molecules, potentially causing damage to living tissue.
Chronic Toxicity
The adverse health effects resulting from long-term exposure to a toxic substance or agent.
- Comprehend the variety of dose-response curve models and their significance in the field of toxicology.
Verified Answer
Answer: B
The linear dose-response model suggests that the risk of damage from a substance or radiation exposure is directly proportional to the dose received. As a result, each dose of ionizing radiation or toxic chemical carries a risk of causing harm.
Answer: C
Threshold dose-response models are best suited for assessing chronic toxicity. Chronic toxicity is characterized by negative effects that occur over a long-term period with low-dose or repeated exposure. As a result, the threshold limit for harmful effects may be lower than for acute toxicity.
Answer: D
Threshold dose-response models tend to err on the side of safety. This means that the threshold limit for harmful effects is set lower than the actual limit, ensuring that individuals are not exposed to potentially hazardous substances or radiation.
Learning Objectives
- Comprehend the variety of dose-response curve models and their significance in the field of toxicology.
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