Which of the following is true about neurofibrillary tangles?

A) The tangles are common in the brains of Alzheimer's patients but rare in people without neurocognitive disorders.
B) The tangles block acetylcholine receptors and prevent the attachment of neurotransmitters.
C) The tangles have been linked to the emotional and behavioral disturbances seen in Alzheimer's patients.
D) The tangles do not appear to affect the flow of nutrients and essential supplies through cells.