Asked by Roksanara Begum on May 11, 2024

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Tracy is debating whether to try MAOIs or tricyclics to treat her depression. In what way are MAOIs and tricyclics very similar in terms of their effect on neurochemistry?

A) They both block dopamine transmission.
B) They both block serotonin transmission.
C) They both augment dopamine transmission.
D) They both increase norepinephrine and serotonin transmission.

MAOIs

Short for Monoamine Oxidase Inhibitors, a class of antidepressant drugs that work by inhibiting the activity of the monoamine oxidase enzyme, thus increasing levels of certain neurotransmitters in the brain.

Tricyclics

A class of antidepressant medications used to treat depressive disorders by affecting neurotransmitter levels in the brain.

Neurochemistry

The study of chemicals, including neurotransmitters and other molecules, that control and influence the nervous system.

  • Identify the neurotransmitter systems targeted by antipsychotic and antidepressant medications.
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Marie BerryMay 15, 2024
Final Answer :
D
Explanation :
Both MAOIs and tricyclics increase the transmission of norepinephrine and serotonin in the brain. MAOIs accomplish this by inhibiting monoamine oxidase, an enzyme that breaks these neurochemicals down. Tricyclics block the reuptake of these neurochemicals, leading to increased levels in the brain.