Asked by Caroline Moore on Apr 26, 2024
Verified
List the following four carboxylic acid derivatives, ester, anhydride, amide, and acid halide, in order of increasing reactivity in nucleophilic acyl substitution reactions. Start with the least reactive derivative.
Nucleophilic Acyl Substitution
A reaction mechanism in which a nucleophile displaces a leaving group attached to an acyl compound, forming a new covalent bond.
Carboxylic Acid Derivatives
A group of organic compounds, including esters, amides, and acid halides, derived from carboxylic acids by replacement of the hydroxyl group with other functional groups.
- Grasp the patterns of reactivity and the processes that govern nucleophilic acyl substitutions in carboxylic acid derivatives.
Verified Answer
LT
Learning Objectives
- Grasp the patterns of reactivity and the processes that govern nucleophilic acyl substitutions in carboxylic acid derivatives.
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