The nurse is caring for a school-aged child who has injured the right leg after a bicycle accident. Which signs and symptoms will the nurse assess for to determine if the child is experiencing a localized inflammatory response?

A) Malaise, anorexia, enlarged lymph nodes, and increased white blood cells
B) Chest pain, shortness of breath, and nausea and vomiting
C) Dizziness and disorientation to time, date, and place
D) Edema, redness, tenderness, and loss of function